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Itching Under Arms at Night: Causes & Treatments

Author: Mr Oliver Eaton BSc (Hons), PG.Cert – Orthopaedic Specialist
Reviewed by: Mr William Sharples BSc (Hons) – Pain Management Expert
Last Updated: September 2025

In this article, you will learn everything you need to know about arthritis in the wrist and the most effective ways to treat it, including an advanced treatment called Prolotherapy.

Introduction to the Condition

Itchy armpits, or itchy skin in the underarm area, are a common and often frustrating problem that can affect anyone. The skin in the armpits is particularly sensitive, making it more prone to irritation and discomfort. Whether the cause is a minor skin condition, an allergic reaction, or a more serious health issue, understanding why your armpits itch is the first step toward finding relief. Itchy armpits can result from a range of factors, including irritated skin, allergies, and underlying health conditions. By learning about the different causes and how they affect the skin, you can take targeted steps to soothe symptoms and restore comfort. In the following sections, we’ll explore how skin conditions, allergies, and health-related issues can contribute to itchy armpits, and what you can do to address them.

What Causes Itching Under Arms at Night?

man scratching his under arms at night

  • Skin irritation: Shaving, friction, or harsh soaps can irritate the sensitive underarm skin, leading to itchy and irritated skin or even a burning sensation.
  • Allergic reactions: Deodorants, antiperspirants, laundry detergents, or fabrics may trigger itching and make your armpits itchy.
  • Excessive sweating (hyperhidrosis): Moisture creates an environment for irritation and infection, and sweat glands clog can occur, increasing the risk of itchy armpit symptoms.
  • Fungal or bacterial infections: Warm, moist armpits are prone to infections like tinea (ringworm) or folliculitis. A fungal infection can cause armpits itchy and may require targeted antifungal treatment to effectively treat itchy armpits [1].
  • Skin conditions: Eczema, psoriasis, and contact dermatitis are common culprits [2].
  • Chronic skin conditions: Persistent itchy and irritated skin can be caused by chronic skin conditions such as eczema, lupus, or other autoimmune diseases, which may require ongoing management.
  • Hormonal changes: Fluctuations during menopause or pregnancy can increase skin sensitivity.
  • Systemic diseases and medical conditions: Diabetes, liver, or kidney disease, as well as other medical conditions, can present with nocturnal itching or itchy skin at night.
  • Medications: Some drugs, including antibiotics and statins, may cause itching as a side effect.
  • Psychological factors: Stress and anxiety can heighten itch perception at night and make you feel itchy.
  • Bed bugs or insect bites: Can cause localized itching that worsens at night.
  • Risk factors: Age, environmental factors, and personal habits can increase the likelihood of experiencing itchy armpit symptoms.

Nocturnal pruritus (itchy skin at night) can be caused by a combination of these factors. Sweat glands can become clogged, leading to irritation, bumps, and a burning sensation under the arms. Maintaining proper hygiene and treating itchy armpits promptly can help prevent complications such as skin infection. Skin cells release histamine, which can make you feel itchy, so addressing the underlying cause is important to effectively treat itchy armpits.

Identifying the underlying cause is crucial for effective treatment.

Skin Conditions and Itchiness

Many people experience itchy armpits as a result of skin conditions such as atopic dermatitis, eczema, or psoriasis. These conditions can cause dry skin, inflammation, and persistent irritation, leading to uncomfortable itchy sensations in the underarm area. Intertrigo, a rash that develops in skin folds like the armpits, is another common culprit. To relieve itchy skin caused by these conditions, it’s important to keep the skin hydrated by using gentle, fragrance-free moisturizers and cleansers. Applying anti-itch creams or topical steroids, as recommended by a healthcare provider, can help soothe itchy armpits and reduce inflammation. By maintaining a regular skincare routine and addressing dryness, you can help prevent flare-ups and keep your skin comfortable.

Allergies and Itchiness

Allergic reactions are a frequent cause of itchy armpits. Ingredients in personal care products such as deodorants, soaps, or laundry detergents can trigger skin irritation and itchiness, especially in those with sensitive skin. Fragrances, preservatives, and other additives are common allergens that may lead to uncomfortable symptoms. Identifying and avoiding these triggers is key to preventing itchy armpits. In addition, allergic reactions to insect bites or stings can also cause localized itching. To relieve itchy skin and reduce inflammation, try applying cold compresses or soothing aloe vera gel to the affected area. These simple remedies can help calm irritated skin and provide much-needed relief.

In some cases, itchy armpits may signal an underlying health issue that requires medical attention. Conditions such as breast cancer, inflammatory breast cancer, or lymphoma can sometimes present with itching in the armpit area, especially if accompanied by other symptoms like severe pain, skin discoloration, or swelling. Skin infections and nerve disorders are additional health-related causes to consider. If your itchy armpits persist, worsen, or are associated with unusual symptoms, it’s important to consult a healthcare provider for a thorough evaluation. Practicing proper hygiene, avoiding harsh chemicals, and choosing gentle skincare products can help prevent itchy armpits and support overall skin health. Always seek professional advice if you suspect an underlying condition.

Symptoms of Itching Under Arms at Night

  • Intense itching, especially in the evening or at bedtime
  • Redness, bumps, or rash in the armpit area
  • Dry, flaky, or thickened skin
  • Burning, stinging, or tenderness
  • Scratching that leads to broken skin or sores
  • Disturbed sleep or insomnia
  • Unpleasant odour (if infection is present)

How Is Nocturnal Pruritus (Underarm Itching) Diagnosed?

Diagnosis starts with a detailed medical history and physical examination. Your clinician may ask about your symptoms, triggers, and any underlying health conditions. They may also inquire about recent or ongoing cancer treatments, as these can be associated with skin symptoms such as itching under the arms. Clinicians will also look for signs of skin infection. Additional tests may include:

  • Skin swabs or scrapings for suspected infections
  • Patch testing for allergies
  • Blood tests to check for diabetes, thyroid, liver, or kidney issues
  • Assessment of hygiene and personal care products

Early and accurate diagnosis is essential for effective treatment [3].

Home Remedies and Self-Care

 

Taking care of your skin at home can make a significant difference in relieving itchy armpits and preventing future discomfort. Start by keeping your skin hydrated with gentle, fragrance-free moisturizers, and use mild cleansers to avoid further irritation. Choose breathable clothing to minimize friction and help control excessive sweating, which can contribute to itchy skin. Practicing good hygiene and steering clear of harsh chemicals in personal care products are essential steps in preventing itchy armpits. If you experience itching, applying anti-itch creams, topical steroids, or cold compresses can help soothe itchy armpits and provide quick relief. Remember, if your symptoms persist or become more severe, it’s important to consult a healthcare provider to rule out any underlying conditions and receive appropriate treatment. By combining self-care with professional guidance, you can effectively manage itchy armpits and maintain healthy, comfortable skin.

Treatments for Itching Under Arms at Night

Woman Scratching her itchy arm pit at night

The best treatment depends on the underlying cause, severity, and your individual needs. Options include:

  • Gentle cleansing: Use mild, fragrance-free soap and avoid scrubbing.
  • Moisturisers: Apply fragrance-free creams or ointments to prevent dryness.
  • Topical steroids: Reduce inflammation in eczema, psoriasis, or allergic reactions.
  • Antifungal or antibacterial creams: For infections, as prescribed by your doctor.
  • Antihistamines: Oral or topical antihistamines can relieve allergic itching and help with sleep.
  • Loose, breathable clothing: Reduces friction and moisture build-up.
  • Addressing underlying conditions: Managing diabetes, thyroid, or liver disease can reduce symptoms.
  • Behavioural strategies: Stress management, mindfulness, and keeping nails short to prevent skin damage.

Prolotherapy

In recent years, Prolotherapy has built its reputation within the medical community for its clinically proven ability to treat itching under arms.

Published research has proven its pain-relieving, anti-inflammatory and regenerative benefits.

Prolotherapy involves injecting a natural regenerative solution with tiny needles. This has been shown to stimulate the production of collagen cells, the small cells needed to help with itching under arms.

As prolotherapy is helping to treat the root cause of itching under arms, it is deemed to be a permanent fix, preventing the symptoms from returning.

Disclaimer: The information provided in this section is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Prolotherapy may not be suitable for everyone, and outcomes can vary. Always seek the guidance of a qualified healthcare professional regarding your specific medical condition or treatment options. Never disregard professional medical advice or delay seeking it because of information you have read here.

Case Study: Lasting Relief from Nocturnal Underarm Itching

Patient: Sarah, 39, fitness instructor
Condition: Chronic nighttime armpit itching due to eczema and recurrent fungal infections
Treatment: 2 sessions of prolotherapy at ProHealth Clinic
Outcome: Sarah reported an 80% reduction in itching and improved sleep within 4 weeks. She remains symptom-free at her 6-month follow-up.

Are Treatments for Underarm Itching Safe?

Most non-surgical treatments, including prolotherapy, are considered safe when performed by experienced clinicians. Side effects are rare but may include temporary redness, swelling, or mild discomfort. Always consult a qualified practitioner to discuss risks and benefits [4].

How to Choose the Right Treatment to Treat Itchy Armpits at Night

The best approach depends on your symptoms, underlying health, and treatment goals. A thorough assessment by a specialist is essential. At ProHealth Clinic, we create personalised treatment plans, often combining therapies for optimal results.

Frequently Asked Questions

Why do my armpits itch more at night?

Nighttime itching is often due to increased skin sensitivity, hormonal changes, and reduced distractions. Warmth, sweating, and friction from bedding can also worsen symptoms.

What is the best cream for itchy armpits at night?

Use a fragrance-free, gentle moisturiser. For inflammatory conditions, a mild topical steroid or antifungal cream may be recommended by your doctor.

Can stress cause itching under arms at night?

Yes, stress and anxiety can heighten itch perception and trigger flare-ups, especially at night.

Is prolotherapy safe for itching under arms?

Yes, prolotherapy is considered safe when performed by trained professionals. Side effects are rare and usually mild.

When should I see a doctor for underarm itching?

See a doctor if itching is severe, persistent, or associated with rash, swelling, or other symptoms. Medical evaluation is important to rule out underlying conditions.

Contact ProHealth Clinic Today for Your FREE 15-Minute Discovery Call

Don’t let itching under arms control your life any longer. Join the thousands of patients who have found lasting relief through prolotherapy at ProHealth Clinic.

Get in Touch
Phone: +441234380345
Email: info@prohealthclinic.co.uk

Our Clinic Locations
London: 104 Harley Street, Marylebone, W1G 7JD
Manchester: The Hadley Clinic, 64 Bridge Street, M3 3BN
Bedford: The Village Medical Centre, Kingswood Way, MK40 4GH

All clinics offer the same award-winning prolotherapy treatment with convenient appointment times, including evenings and weekends.

Author Bio

Having performed over 10,000 procedures, Mr Oliver Eaton is one of the UK’s leading practitioners in the field of treating itching under arms, with patients travelling to see him from across the UK, Europe, and the Middle East.

With over 12 years of clinical experience, Oliver is dedicated to helping patients understand their symptoms associated with itching under arms and providing effective treatment options to alleviate them.

He qualified in Prolozone Therapy and Prolotherapy in America with the American Academy of Ozonotherapy. He continued on to complete further qualifications at the Royal Society of Medicine, Charing Cross Hospital in London, Keele University’s Anatomy & Surgical Training Centre, and the medical department of Heidelberg University in Germany.

Over the years he has had the privilege of treating many elite-level athletes, including both Olympic and Commonwealth medallists.

Mr Eaton’s expertise has been featured in many national news and media publications, including The TelegraphThe Daily MailThe Daily Express, Women’s Health Magazine, and The Scotsman.

Linkedin profile

References

  1. Kong HH, et al. Bacterial and fungal infections in the axilla. J Am Acad Dermatol. 2012;66(3):e109-e120. Link
  2. Ständer S, et al. Clinical classification of itch: a position paper of the International Forum for the Study of Itch. Acta Derm Venereol. 2007;87(4):291-294. Link
  3. Weisshaar E, et al. Epidemiology of chronic pruritus: where do we stand? Front Med. 2021;8:644119. Link
  4. Rabago D, et al. Prolotherapy in primary care practice. Prim Care. 2010;37(1):65-80. Link

Disclaimer: This article is for informational purposes only and does not substitute for professional medical advice. Always consult your healthcare provider before making treatment decisions.

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