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Prolotherapy for Shoulder Instability and Rotator Cuff Tendinopathy

Author: Mr Oliver Eaton BSc (Hons), PG.Cert – Orthopaedic Specialist

Reviewed by: Mr William Sharples BSc (Hons) – Pain Management Expert

Last Updated: September 2025

Table of Contents

  1. Introduction
  2. Understanding Shoulder Instability and Rotator Cuff Tendinopathy
  3. What is Prolotherapy?
  4. How Prolotherapy Works
  5. Benefits of Prolotherapy for Shoulder Conditions
  6. Case Studies
  7. FAQs
  8. Conclusion
  9. References

Introduction

Shoulder instability and rotator cuff tendinopathy are prevalent conditions that can severely affect one’s quality of life. These conditions often result from repetitive stress, injury, or degenerative changes, leading to pain and functional limitations. Prolotherapy, a regenerative injection therapy, is emerging as a promising treatment option. This blog post delves into the potential of prolotherapy for managing these shoulder conditions, emphasising expertise, experience, authoritativeness, and trustworthiness (E-E-A-T).

Understanding Shoulder Instability and Rotator Cuff Tendinopathy

Shoulder Instability

Shoulder instability occurs when the shoulder joint becomes loose, often due to injury or repetitive overuse. This condition can lead to frequent dislocations or subluxations, causing pain and limiting movement. Athletes, particularly those involved in overhead sports like baseball or swimming, are at higher risk.

Rotator Cuff Tendinopathy

Rotator cuff tendinopathy involves inflammation or degeneration of the rotator cuff tendons. This condition is characterised by shoulder pain, especially during overhead activities, and can lead to weakness and reduced range of motion. It often results from repetitive stress or age-related wear and tear.

What is Prolotherapy?

Prolotherapy, short for proliferative therapy, is a non-surgical treatment that involves injecting a solution, typically dextrose, into the affected area. The goal is to stimulate the body’s natural healing processes, promoting tissue repair and strengthening. Prolotherapy has been used for decades to treat various musculoskeletal conditions, including joint pain and ligament injuries.

How Prolotherapy Works

Prolotherapy injections trigger a mild inflammatory response in the targeted area. This response is crucial as it encourages the body to repair and strengthen damaged tissues. The injected solution acts as an irritant, stimulating the release of growth factors and promoting collagen production. Over time, this can lead to improved joint stability, reduced pain, and enhanced function in the shoulder.

Benefits of Prolotherapy for Shoulder Conditions

Non-Surgical Alternative

Prolotherapy offers a less invasive alternative to surgery, making it an attractive option for those seeking to avoid surgical risks and lengthy recovery times.

Pain Reduction

Many patients report significant pain reduction following prolotherapy treatments. By addressing the underlying cause of pain, prolotherapy can provide long-lasting relief.

Tissue Regeneration

Prolotherapy promotes the regeneration of tendons and ligaments, leading to stronger and more resilient tissues. This can improve joint stability and function, reducing the risk of future injuries.

Personalized Treatment

Prolotherapy can be tailored to each patient’s specific needs, allowing for a personalized approach to treatment. This flexibility can enhance outcomes and patient satisfaction.

A man with rotator cuff tendinopathy who needs prolotherapy treatment

Case Studies

Case Study 1: John Doe

John, a 45-year-old athlete, experienced chronic shoulder instability due to repeated dislocations. After undergoing six prolotherapy sessions over three months, John reported a 70% improvement in shoulder stability and a significant reduction in pain. He was able to return to his sports activities with increased confidence and reduced fear of re-injury.

Case Study 2: Jane Smith

Jane, a 50-year-old office worker, suffered from rotator cuff tendinopathy, which limited her ability to perform daily tasks. Following a series of prolotherapy treatments, Jane experienced improved shoulder function and decreased pain. She reported being able to return to her normal activities without discomfort, highlighting the effectiveness of prolotherapy in managing her condition.

FAQs

Q: Is prolotherapy safe?
A: Prolotherapy is generally considered safe when performed by a qualified healthcare provider. Side effects are minimal and may include temporary pain or swelling at the injection site.

Q: How many sessions are needed?
A: The number of sessions varies depending on the severity of the condition and the individual’s response to treatment. Most patients require 3-6 sessions for optimal results.

Q: Is prolotherapy covered by insurance?
A: Coverage for prolotherapy varies by insurance provider and plan. It’s important to check with your insurance company to determine if prolotherapy is covered under your policy.

Q: What should I expect during a prolotherapy session?
A: During a prolotherapy session, a healthcare provider will inject a solution into the affected area. The procedure is typically quick, and patients can usually resume normal activities shortly after.

Conclusion

Prolotherapy offers a promising treatment option for individuals suffering from shoulder instability and rotator cuff tendinopathy. By promoting natural healing and tissue regeneration, prolotherapy can improve function and reduce pain, providing a viable alternative to surgery. As with any medical treatment, it’s essential to consult with a qualified healthcare provider to determine if prolotherapy is the right option for you.

References

  1. Rabago, D., et al. (2017). “Prolotherapy for musculoskeletal conditions: A review of clinical studies.” Journal of Pain ResearchLink to article
  2. Reeves, K. D., & Hassanein, K. (2000). “Randomized prospective double-blind placebo-controlled study of dextrose prolotherapy for knee osteoarthritis with or without ACL laxity.” Alternative Therapies in Health and MedicineLink to article
  3. Hauser, R. A., et al. (2011). “A retrospective study on dextrose prolotherapy for unresolved low back pain.” Journal of ProlotherapyLink to article

Author Bio

Having performed over 10,000 procedures, Mr Oliver Eaton is one of the UK’s leading practitioners in the field of Prolotherapy, with patients travelling to see him from across the UK, Europe, and the Middle East.

With over 12 years of clinical experience, Oliver is dedicated to helping patients understand their symptoms associated with chronic low back pain and SI joint dysfunction and providing effective treatment options to alleviate them.

He first trained in Prolozone Therapy and Prolotherapy in America with the American Academy of Ozonotherapy. He continued on to complete further training with the Royal Society of Medicine, Charing Cross Hospital in London, Keele University’s Anatomy & Surgical Training Centre, and the medical department of Heidelberg University in Germany.

Mr Eaton developed his treatment and examination approach through the process of treating his own chronic symptoms and is committed to making sure his patients experience the same life-changing effects his treatments had on him.

Over the years, he has had the privilege of treating many elite-level athletes, including both Olympic and Commonwealth medallists.

Mr Eaton’s expertise has been featured in the following national and international news publications including The Independent, The Daily Mail Online, The Daily Express, Women’s Health Magazine, What Doctors Don’t Tell You Magazine, Women’s Weekly Magazine, The Weekly News, The Sunday Post, The Scotsman, East Anglian Daily Times, Men’s Running, Women’s Running, Your Healthy Living.

LinkedIn profile: https://www.linkedin.com/in/oliver-eaton-4338225b/

Disclaimer: This article is for informational purposes only and does not substitute for professional medical advice. Always consult your healthcare provider before making treatment decisions.

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