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Ozone Injection Therapy

Prolozone Therapy: An Advanced Form Of Ozone Injection Therapy

About Prolozone Therapy

Medical Ozone injection therapy has built a reputation for achieving results when all other treatments have failed. The treatment is used to relieve pain, repair, strengthen and regenerate the following structures: joints, cartilage, spinal discs, muscles, ligaments, tendons, meniscus, and bursa.

The treatment was named ‘Prolozone Therapy’ because it involves the injection of medical ozone and nutrients to proliferate cells in a weak or damaged region of the body. To proliferate cells means to multiply and increase the number of them.

Prolozone Therapy proliferates chondrocyte and collagen cells. Cartilage is formed mainly of chondrocytes. Spinal discs (involved in back pain), muscles, ligaments, tendons, meniscus, and bursa are formed mainly of collagen. The treatment increases the number of these cells through activating chondroblasts and fibroblasts, which are the pre-curser building blocks to chondrocytes and collagen.

Medical Ozone injection therapy has the ability to provide complete relief of symptoms, even in severe conditions that have been present for many years. The treatment is naturally anti-bacterial, so deemed one of the safest injections on offer within medicine.

Prolozone Therapy works on just about any pain problem you might have, including:

  • Arthritis of any joint (Osteoarthritis or Rheumatoid Arthritis)
  • Neck pain
  • Back pain
  • Hip pain
  • Spinal disc herniations (bulges)
  • Shoulder pain
  • Elbow pain
  • Wrist or hand pain
  • Foot and ankle pain
  • Knee pain
  • Tendon & ligament injuries
  • Fibromyalgia
  • Sacroiliac joint (SI Joint) pain and pelvic instability
  • Sternoclavicular (SC) joint pain
  • Hypermobility Syndromes
  • Acromioclavicular (AC) joint pain
  • Headaches and Migraines
  • virtually any injury or condition in the body causing pain and dysfunction

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Frequently Asked Questions

The therapeutic use of medical ozone injections dates back as far as World War 1 when German doctors used it in the trenches to disinfect wounds. Since then, research and many clinical reviews have shown the medical treatment to have a variety of health benefits.

What is ozone injection therapy?

Ozone therapy is a form of oxygen therapy and alternative medicine that involves the use of medical ozone to treat different medical conditions.

Ozone is made up of three oxygen atoms and is referred to as O3 in chemistry.

Ozone gas is naturally occurring in the earth’s atmosphere and helps to protect us from UV radiation.

There are three main types of healthcare treatment options that involve medical ozone:

Orthopaedic ozone injection – A procedure that involves the injection of medical ozone gas into a damaged, weak, or painful area of the body.

Autohemotherapy –  This treatment involves 150ml of venous blood being taken out from a patient and then mixed with medical ozone before being reinfused back into the vein. It provides maximum oxygenation to body tissues. Intramuscular injections can also be performed.

Ozonated oil – An oil infused with ozone gas to use topically on the skin. It is typically used for wound care or skin problems. The most common ozonated oils used are olive oil and coconut oil.

Medical use of ozone therapy

Pain relief and injury

The therapeutic effect of ozone injections helps to stimulate the healing compounds needed to repair.

The reason many injuries struggle to heal is due to a lack of blood flow. Cartilage, ligaments, tendons and spinal discs are the main structures in the body that are known to have a poor blood supply.

Chronic muscle injuries involved in back pain can also struggle to receive adequate levels of blood to heal.

The main component of our blood supply that is responsible for stimulating the repair process is oxygen. The injection of medical ozone helps to provide a direct supply of oxygen to injured structures, alongside its anti-inflammatory properties.

A medical ozone injection can have a therapeutic effect on the following injuries:

Osteoarthritis of any joint, back pain, neck pain, hip pain, knee pain (including knee osteoarthritis), shoulder pain, foot & ankle pain, wrist & hand pain, SI-Joint pain, spinal herniated discs (this include both cervical and lumbar disc herniation), tendon & ligament injuries, and fibromyalgia.

An ozone injection can treat almost any injured and painful part of the body. If your condition hasn’t been listed and you are unsure about whether we can help or not, please call us or send an email to info@prohealthclinic.co.uk.

Immune system disorders

Our body produces cytokines in response to an infection or cancer. Cytokines are messengers that help other cells to communicate.

Our immune system relies on cytokines to kill bacteria, cancer cells, and prevent viral replication. Oxygen-Ozone therapy helps to increase the production of a wide variety of cytokines. The treatment can be beneficial for people with autoimmune disorders.


Medical ozone has natural antibacterial properties and helps to boost the levels of a major detoxification enzyme called glutathione. Alongside detoxification, glutathione also has the following benefits:

  • Supports immune function and quality of life.
  • It helps to break down free radicals.
  • Increases antioxidant (superoxide dismutase) capability.
  • It helps to transport mercury and other forms of toxicity out of the brain.
  • Assist the gallbladder and liver in dealing with fats.

By detoxifying bad bacteria and foreign substances out of the body, our immune system is able to function better.

Breathing disorders

Ozone therapy can be used to treat a variety of breathing disorders. It reduces the stress on the lungs by providing more oxygen to the blood. Clinical trials have shown promise for the following conditions:

  • Chronic obstructive pulmonary disease (COPD)
  • Asthma


Ozone therapy has been shown to reduce the risk of complications with people suffering from diabetes.

The majority of complications are primarily caused by oxidative stress and a decrease in blood supply to certain body tissues, particularly the hands and feet.

Oxidative stress occurs when the body becomes overwhelmed by the harmful effects of free radicals due to a lack of antioxidants.

Also, wounds struggle to heal very quickly in people with diabetes so ozone therapy can help to speed up the repair process.

Heart disease

A study has shown positive effects on the use of ozone therapy with people suffering from ischemic heart disease. It found that it is useful during the acute phase of infarctions.

Wound healing

Medical ozone treatment helps to increase growth factors in both acute and chronic wounds, alongside it’s anti-inflammatory effects.

Macular degeneration

Several studies have shown that ozone therapy can halt the progression of macular degeneration.

Bacterial and fungal infections

Ozone therapy has been shown in studies to destroy the cell walls of bacteria and inhibit the growth of fungi. Lyme disease is one of the most common bacterial conditions to be treated by the therapy.

How do you produce medical ozone?

Ozone generators are used to produce medical ozone. They do this by breaking apart medical oxygen into single atoms. The atoms then attach to other oxygen molecules to form ozone.

Side effects of an ozone injection

An individual may experience mild pain and discomfort around the injection site for a few days as part of the repair process.

It is normal to experience mild bruising around the injection site.

If a person is using ozone therapy for detoxification purposes then it is common to experience side effects such as temporary headaches and increased urination as the body is flushing bad bacteria out of the system.

It is not advised to breathe in ozone gas as it is an oxidant and classed as a toxic gas to lung tissue.

Other facts about ozone

  • Ozone is used as a disinfectant for foods in restaurants.
  • Ozonation of water in swimming pools can be used as a purification method.
  • Drinking water can also be ozonated.
  • It is not regulated by the food and drug administration (FDA).
  • Ozone smog is a chemical reaction between nitrogen oxides and organic compounds.
  • Ozone saunas are another way of experiencing the beneficial effects of ozone therapy.
  • The most well known scientists showing the efficacy of ozone are J.S. Ekta, A.M. Elvis, and Professor Bocci V, Borrelli e.
  • Ozone does not affect red blood cell enzymes or red blood cell integrity.
  • There are many meta-analysis studies on pubmed and google scholar proving the effects of ozone injections in healthcare.
  • The substance is anti-viral.
  • There have been a small number of studies showing the effect that the treatment can have against coronavirus.
  • There are also many applications used in dentistry.

Interested to find out how much medical ozone injection therapy costs?