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Prolotherapy: Achieving Results When All Else Has Failed

Prolozone Therapy: An Advanced Form Of Prolotherapy

About Prolozone Therapy

What is Prolozone Therapy? It is an advanced form of prolotherapy in the UK which has built a reputation for achieving results when all other treatments have failed. Studies have proven that it can relieve pain, repair, strengthen and regenerate the following structures: joints, cartilage, spinal discs, muscles, ligaments, tendons, meniscus, and bursa.

The treatment was named ‘Prolozone Therapy’ because it involves the injection of medical ozone and nutrients to proliferate cells in a weak or damaged region of the body. To proliferate cells means to multiply and increase the number of them.

Prolozone Therapy proliferates chondrocyte and collagen cells. Cartilage is formed mainly of chondrocytes. Spinal discs, muscles, ligaments, tendons, meniscus, and bursa are formed mainly of collagen. The treatment increases the number of these cells through activating chondroblasts and fibroblasts, which are the pre-curser building blocks to chondrocytes and collagen.

Prolozone Therapy has the ability to provide complete relief of symptoms, even in severe conditions that have been present for many years. Medical Ozone is naturally anti-bacterial, so deemed one of the safest injections on offer within medicine.

Prolozone Therapy works on just about any pain problem you might have, including:

  • Arthritis of any joint (Osteoarthritis or Rheumatoid Arthritis)
  • Neck pain
  • Back pain
  • Hip pain
  • Spinal disc herniations (bulges)
  • Shoulder pain
  • Elbow pain
  • Wrist or hand pain
  • Foot and ankle pain
  • Knee pain
  • Tendon & ligament injuries
  • Fibromyalgia
  • Sacroiliac joint (SI Joint) pain and pelvic instability
  • Sternoclavicular (SC) joint pain
  • Hypermobility Syndromes
  • Acromioclavicular (AC) joint pain
  • Headaches and Migraines
  • virtually any injury or condition in the body causing pain and dysfunction

What is the difference between Prolozone and standard Prolotherapy?

Prolozone Therapy uses a regenerative form of oxygen (Medical Ozone) to stimulate repair and regeneration. Standard Prolotherapy injections use an irritant in the form of sugar (dextrose solution) to cause an inflammatory response. This inflammatory response helps to stimulate healing but has the following limitations: Standard dextrose prolotherapy injections can be extremely painful and sometimes requires gas and air during the procedure. The pain experienced during a Prolozone injection procedure is minimal.

It takes much longer to reach the repair phase with standard prolotherapy, meaning that prolozone achieves results in a faster time-frame.

Standard Prolotherapy requires many injections, whereas Prolozone only requires a few, making it much less expensive for the patient.

Prolozone also has the ability to spread further around the site of injection, meaning it not only has a positive effect on the injury itself, but also the surrounding tissues that may also have been under strain due to compensation.

For example, a patient comes into the clinic with knee or hip arthritis. Prolozone will not only reduce pain, inflammation, and aid the regeneration of cartilage within the joint, but it will also help to repair and strengthen other neighbouring structures around it. These other structures include ligaments, muscles and tendons that would have been put under additional strain from the instability that arthritis causes within a joint.

Or if a patient has a spinal disc injury, Prolozone will also have a positive effect on the supporting spinal joints, muscles, ligaments and tendons that are attached around the injured disc.

The health of the structures that are attached around an injury, will always determine the results achieved with an injection, and the ability for those results to last. This is why Prolozone in our clinic has been shown to achieve results where standard prolotherapy has either failed or only provided temporary relief.

PRACTITIONER - Mr Oliver Eaton BSc (Hons) Ost Med, PG.Cert

Having performed over 4000 injection procedures, Oliver is one of the UK’s leading practitioners in the field of prolotherapy, with patients traveling to see him from across the UK, Europe, and the Middle East.

He first trained in Prolozone and Prolotherapy in America and continued on to complete further injection training with the Royal Society of Medicine, Charing Cross Hospital in London, and the medical department of Heidelberg University in Germany.

Having also completed a 4-year degree in Osteopathic Medicine, Oliver has extensive training in identifying and treating misalignments, imbalances, and areas of inflammation in the body that fail to show up on MRI and X-ray scans.

Spending up to 75 minutes during each appointment with his patients gives Oliver the time to carefully identify and treat these issues during the same appointment as the injections. This combined approach significantly enhances the injection treatment results.

The enhancement not only accelerates the repair process but also helps to prevent any symptoms from returning. Oliver uses the latest computerized biomechanical analysis technology to help identify misalignments and additional areas of inflammation in the body.

This integrated approach to examination and treatment significantly reduces the number of appointments a patient needs, compared to a practitioner who performs only Prolotherapy or only Prolozone during an appointment. Oliver developed his treatment approach through the process of treating his own chronic pain and is committed to making sure that his patients experience the same life-changing effects that his treatments had on him.

During his time practising prolotherapy Oliver has had the privilege of treating many elite athletes including Olympic and Commonwealth medalists.

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Frequently Asked Questions

What is the success rate?

Our clinical audits show that 95% of our patients experience results with our treatment.

Our success rate is higher than what is typically stated in studies, as we often combine the treatment with other rehabilitation therapies within the same appointment as the injections to enhance the results. These therapies include advanced orthopaedic massage, stretching, and strengthening techniques.

For the 5% of patients that don’t experience any results or pain relief, we help to point them in the right direction of another practitioner or therapy that may be able to help.

How long does it take for the treatment to work?

The speed at which an individual starts to experience symptom relief is all dependant on the type of pain condition that they come in to see us with.

Some patients start to experience relief after a few hours, some after a few days, and some not until a few weeks after their third follow-up appointment. 80% of patients will start to experience results after just one appointment.

What happens during a Prolotherapy consultation and examination?

Your practitioner will start by taking down a full medical case history. This will involve asking you detailed questions about your current symptoms, and any previous conditions or incidents that may have had an influence.

Many individuals come to see us because they have failed to experience relief with other therapies. Sometimes we find that the issue wasn’t necessarily with the other therapies themselves, but the fact that the practitioner performing that therapy may not have accurately assessed and examined the individual properly to start with, and therefore not applied the therapy appropriately.

This is why we conduct a thorough examination using computerized biomechanical technology to help identify issues and imbalances in the body that previous practitioners may not have identified. The information that our technology provides, helps us to perform more targeted and effective treatment for our patients.

Is prolotherapy offered on the NHS?

Unfortunately, the treatment isn’t offered on the NHS at this point in time.

What is the recovery period after each injection?

Most patients are able to go about their daily activities straight away after the treatment. It is advised to modify any strenuous activity for a few days.

Are there any side effects?

It is normal to experience pain and discomfort around the injection site for a few days as part of the repair process, but it shouldn’t stop you from continuing on with your daily activities.

It is common to experience temporary bruising at the injection site. Using an ice pack may help for the first 6-12 hours after the procedure. Then, only heat is helpful in the healing process.

Do you prescribe any exercises to perform alongside Prolotherapy?

If appropriate, we will provide specific physical therapy exercises for you to perform at home in between each appointment. These exercises will help to enhance the effect of prolotherapy and prolozone treatment.

Do I have to avoid doing anything after the treatment?

We advise you to avoid public hot tubs, swimming pools, and lakes for 3 days following each appointment to avoid any bacteria getting near the injection site. A shower or bath at home within this time is fine.

How safe is the treatment?

Medical Ozone, the main ingredient of Prolozone, has been shown to be one of the safest substances used within medicine.

According to the International Scientific Committee of Ozone Therapy: Medical Ozone is not a drug and as such it does not cause side effects, does not cause allergic reactions and in general, there are no interactions with other drugs.

When administered in prescribed amounts by a qualified practitioner, the chances of experiencing adverse reactions are extremely small. For example, a German study on 384,775 patients evaluating the adverse side effects of over five million medical ozone treatments found that the rate of adverse side effects was only 0.0007 per application. This figure is far lower than any other type of medical treatment.

Will I get treatment on the first visit?

We always leave enough time during your first visit for treatment. If you are a complex case and require multiple areas treating, then please notify the receptionist upon booking, as you may require a double-slot appointment.

How do Prolotherapy and Prolozone injections compare to the injections offered to me by my local doctor?

Many of the injections offered by your local doctor only have the ability to temporarily reduce inflammation and cover up the pain, with many potential negative side effects that can reduce the health of connective tissue in the body. Many of these negative side effects have been reported in a recent study performed at the medical department of Boston University.

In comparison, Prolozone injections aim to not only reduce inflammation and pain but primarily repair and strengthen a damaged or weak area of the body. Prolozone injections have an excellent safety profile and DO NOT have the same negative side effects as the injections offered by your doctor.

How long has the treatment been around?

Medical Ozone injection therapy has been used in Europe since the 1950s. It is most commonly used in Germany with over 7000 practitioners offering the treatment to help provide chronic musculoskeletal pain relief. In parts of Italy, it is included as a medical treatment in their own national health service.

How does it help to repair and regenerate?

According to the International Scientific Committee of Ozone Therapy: Different data coming from scientific research recognizes that a medical ozone injection has a dual-action mechanism: analgesic and anti-inflammatory.

These effects seem to be due to its way of acting on diverse targets: 1) Decrease the production of mediators of the inflammation. 2) The oxidation (inactivation) of metabolic mediators of pain. 3) It clearly improves local blood microcirculation, with an improvement in the oxygen delivery to the tissues, essential for the regeneration of anatomic structures; the elimination of toxins, and in general to the resolution of the physiological disturbance that generated the pain.

There are many systematic reviews and randomized controlled trials proving the effects of prolotherapy treatment for joint pain. Research presented at a meeting at the American College of Rheumatology outlined the improvements in pain, mobility, and overall wellbeing with the use of medical ozone injections for knee osteoarthritis.

How does the treatment help cartilage?

‘Once articular cartilage is damaged, it has limited potential to repair itself. Many treatment modalities that are used to repair damaged articular cartilage show limited efficiency. Medical ozone, the main ingredient of Prolozone Therapy, has shown to be effective in the treatment of damaged articular cartilage in osteoarthritis.

A medical ozone injection inhibits the inflammatory milieu which damages the cartilage matrix and induces apoptosis of chondrocytes. It produces its beneficial effects by normalizing the cellular redox balance and through the actions of cytokines.’ Please refer to the following scientific review

My doctor said that Prolozone Therapy or Prolotherapy isn’t going to help me.

Unfortunately, many doctors in the UK don’t fully understand how prolozone and prolotherapy works. This is because it isn’t part of their original medical training.

If they think that the treatment is new, it shows they do not understand the decades of research and patient results supporting its use for the treatment of chronic pain, sports injuries, and osteoarthritis.

How does Prolozone Therapy help to heal spinal discs?

To treat spinal discs we adopt a specific method developed by a doctor called Dr. Cesare Verga. This method is called the ‘Discosan Method’.

To understand how the method works, it is important to understand the anatomy of a spinal disc. It is comprised of two main sections: an outer band called the annulus fibrosus, and an inner gel-like structure called the nucleus pulposus. A herniation develops when fibres rupture in the outer rings of the annulus fibrosus. This then causes the inner nucleus pulposus to protrude and compress a nerve root. This compression is what causes the pain associated with a herniated disc.

How does the Discosan Method help?

  1. The method helps to undo the bonds holding the herniation together, in turn reducing the size of the herniation.
  2. It reduces swelling in the area, which helps to take further pressure off the nerve root.
  3. The method helps to improve micro-circulation in the disc, therefore increasing the level of oxygen and nutrients to assist the healing of the ruptured fibres.

A study published in the International Journal of Spine Surgery in 2014 claims to be the first to look at how patients are doing long-term after medical ozone spinal injections—five and 10 years later. Based on MRI scans, 79 percent of patients had a reduction in herniation volume, and the average reduction was 56 percent.

Among the 108 patients who underwent medical ozone treatment in the study, 89 did not have any subsequent back surgery, and in this group, 82 percent had improvement at five years, and 88 percent had improvement at 10 years after receiving the ozone injections. Since the ozone injections were also very safe, the researchers concluded that “the risk-reward profile for this treatment is favorable.”

Do you offer dietary advice to help my body repair?

Yes, we provide dietary recommendations that help to enhance the effects of prolotherapy and prolozone therapy, alongside speed up the repair process.

What forms of payment are accepted?

We accept all forms of debit and credit card payments, including American Express. Apple Pay. Cash. Cheque.

Can I claim for Prolotherapy on my health insurance?

While we don’t hold any associations with any health insurance providers, we will provide you with a detailed receipt of payment that can be submitted to a private health insurance provider. Occasionally, we have had patients who have said that they have been reimbursed for prolotherapy by their provider.

Am I too old for a prolotherapy procedure?

We have treated patients well into their 80’s with great success. The more we can keep our elderly patients mobile and without pain, the more they can keep active and independent, which in turn keeps the rest of their physical and emotional health well. Many of our elderly patients come to see us after being told that they are too old for surgery due to the risks involved. We have found that Prolozone Therapy is a great pain management alternative to surgery and painkillers for seniors suffering from chronic pain.

Can the treatment help with ligament laxity?

The use of prolotherapy for ligament laxity began in the 20th century with Dr. George Hackett and Dr. Gustav Hemwall. Prolotherapy works by creating a healing response to stimulate growth factors within connective tissue in order to improve its strength. Previous soft tissue injuries such as sprains and degenerative conditions such as knee osteoarthritis can cause ligament laxity. Other procedures such a platelet-rich plasma (PRP) can also help ligament laxity but not as effectivity as dextrose injections and prolozone.

Do you have more information about how the treatment helps specific areas of the body?

Yes. We have separate pages on how Prolotherapy and Prolozone therapy help the following areas of the body:

Click on the ‘media and press’ section of our website and then onto the ‘infographics’ section.

There are parts of the body that we don’t have any separate pages for but can still help with. These include elbow, wrist, hand, feet, SI joints. If there is a part of the body that isn’t listed, then please contact us to confirm whether we can help.

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